唐和斌：教授、博士生導(dǎo)師

出生年月：1970.11        民族：漢族

學(xué)歷學(xué)位：藥學(xué)博士      學(xué)科專(zhuān)業(yè)：藥理學(xué)

電話(huà)： 027-67842332     

電子郵箱：[email protected]

研究方向包括：肝損傷機(jī)制及民族藥物干預(yù)；皮膚創(chuàng)傷修復(fù)的民族藥物藥理學(xué)機(jī)制研究。

唐和斌教授，博士生導(dǎo)師，擁有醫(yī)學(xué)學(xué)士學(xué)位和藥學(xué)博士學(xué)位。2005年4月至2009年3月，擔(dān)任日本國(guó)立廣島大學(xué)藥學(xué)院助理教授。2009年4月回國(guó)后，擔(dān)任中南民族大學(xué)藥學(xué)院教授。

主要從事針對(duì)肝損傷（涵蓋脂肪肝、肝纖維化、肝癌等慢性肝?。┘捌つw創(chuàng)傷（包括燒燙傷、糖尿病足潰瘍、銀屑病、特應(yīng)性皮炎、痤瘡、妊娠紋等皮膚屏障損傷性疾?。┑陌l(fā)病機(jī)制研究，同時(shí)致力于這些疾病的民族藥物干預(yù)及其藥理效應(yīng)機(jī)制的深入剖析。尤其在糖尿病足潰瘍、燒傷、妊娠紋等臨床創(chuàng)傷修復(fù)領(lǐng)域的科學(xué)難題上取得了突破性進(jìn)展，成功構(gòu)建了“快速無(wú)痕修復(fù)”這一獨(dú)特的科技壁壘。

作為項(xiàng)目負(fù)責(zé)人，先后主持日本和中國(guó)的國(guó)家自然科學(xué)基金項(xiàng)目6項(xiàng)，以及省部級(jí)科研項(xiàng)目和企業(yè)委托項(xiàng)目近30項(xiàng)。在Journal of Ethnopharmacology、Neuropharmacology等期刊上發(fā)表80余篇論文；獲得授權(quán)的國(guó)家發(fā)明專(zhuān)利28項(xiàng)，其中15項(xiàng)已經(jīng)完成了科技成果轉(zhuǎn)化。

近五年的代表性研究論文（*為通訊作者）

1.      Ma SY, Yin X, Zhang Z, Li YS, Tang HB*. Topical frankincense treatment on relieving high-risk diabetic foot in rats by reducing inflammation and improving microcirculation. Frontiers in Pharmacology. 2025, 16: 1564236. doi: 10.3389/fphar.2025.1564236. eCollection 2025.

2.      Li TT, Wen LY, Meng SS, Li YS, Tang HB*. Oral administration of ethanol extract from Gynura procumbens stems corrects kidney injury and renal anemia in chronic kidney disease. Frontiers in Pharmacology. 2025, 15:1476735. doi: 10.3389/fphar.2024.1476735. eCollection 2024.

3.      Zhang Z, Ma SY, Yin X, Li YS, Tang HB*. Topical frankincense treatment for frostbite based on microcirculation improvements. Journal of Ethnopharmacology. 2025, 336:118728. doi: 10.1016/j.jep.2024.118728.

4.      Yin X, Gu HW, Ning D, Li YS, Tang HB*. Testosterone Exacerbates the Formation of Liver Cancer Induced by Environmental N-Nitrosamines Exposure: Potential Mechanisms and Implications for Human Health. OncoTargets and Therapy. 2024, 17: 395-409. doi: 10.2147/OTT.S456746.

5.      Zhai SY, Gu HW, Wang C, Li YS, Tang HB*. Gynura procumbens and selected metabolites: Amelioration of depressive-like behaviors in mice and risperidone-induced hyperprolactinemia in rats. Biomed Pharmacother. 2024, 173: 116361. doi: 10.1016/j.biopha.2024.116361.

6.      Yin X, Li YS, Ye SZ, Zhang T, Zhang YW, Xi Y, Tang HB. Promotion Effect of Coexposure to a High-Fat Diet and Nano-Diethylnitrosamine on the Progression of Fatty Liver Malignant Transformation into Liver Cancer. International Journal of Molecular Sciences. 2023, 24(18): 14162. doi: 10.3390/ijms241814162.

7.      Meng SS, Gu HW, Zhang T, Li YS, Tang HB*. Gradual deterioration of fatty liver disease to liver cancer via inhibition of AMPK signaling pathways involved in energy-dependent disorders, cellular aging, and chronic inflammation. Frontiers in Oncology. 2023, 13: 1099624. doi: 10.3389/fonc.2023.1099624.

8.      Yin X, Hong J, Tang HB*, Liu M, Li YS. Enhanced healing of oral chemical burn by inhibiting inflammatory factors with an oral administration of shengFu oil. Frontiers in Pharmacology. 2022, 13: 913098. doi: 10.3389/fphar.2022.913098.

9.      Wang C, Huang XL, Mu YM, Li YS, He YM, Tang HB*. Synergistic effects of trans-p-coumaric acid isolated from the ethanol extract of Gynura procumbens in promoting intestinal absorption of chlorogenic acid and reversing alcoholic fatty liver disease. Journal of Ethnopharmacology. 2022, 295: 115407. doi: 10.1016/j.jep.2022.115407.

10.  Zhang T, Gu HW, Gao JX, Li YS, Tang HB*. Ethanol supernatant extracts of Gynura procumbens could treat nanodiethylnitrosamine-induced mouse liver cancer by interfering with inflammatory factors for the tumor microenvironment. Journal of Ethnopharmacology. 2022, 285: 114917. doi: 10.1016/j.jep.2021.114917.

11.  Li YS, Zhang J, Tian GH, Shang HC, Tang HB*. Kirenol, darutoside and hesperidin contribute to the anti-inflammatory and analgesic activities of Siegesbeckia pubescens makino by inhibiting COX-2 expression and inflammatory cell infiltration. Journal of Ethnopharmacology. 2021, 268: 113547. doi: 10.1016/j.jep.2020.113547.

12.  Hong J, Chen XZ, Peng YG, Zhang WK, Tang HB*, Li YS. Nanoparticle-Encapsulated Liushenwan Could Treat Nanodiethylnitrosamine-Induced Liver Cancer in Mice by Interfering With Multiple Critical Factors for the Tumor Microenvironment. Frontiers in Pharmacology. 2020, 11: 1052. doi: 10.3389/fphar.2020.01052.

13.  Zheng L, Li XY, Huang FZ, Zhang XT, Tang HB*, Li YS, Zhang WK, Li XJ, Tian GH. E?ect of electroacupuncture on relieving central post-stroke pain by inhibiting autophagy in the hippocampus. Brain Research. 2020, 1733: 146680. DOI: 10.1016/j.brainres.2020.146680.

近年主持的國(guó)家自然科學(xué)基金項(xiàng)目

1. 基于β-catenin/COX-2炎性環(huán)路探究外用生膚油促進(jìn)糖尿病足病快速修復(fù)的效應(yīng)機(jī)制，2021年國(guó)家自然科學(xué)基金面上項(xiàng)目；

2. 平臥菊三七干預(yù)“β-catenin/COX-2”炎性環(huán)路的防治肝癌機(jī)制研究. 2016年國(guó)家自然科學(xué)基金面上項(xiàng)目；

3. 生膚油促進(jìn)Ⅲ度燙傷皮膚無(wú)瘢痕修復(fù)的機(jī)制研究。2013年國(guó)家自然科學(xué)基金面上項(xiàng)目；

4. Wnt/β-catenin信號(hào)通路調(diào)控原發(fā)性肝癌發(fā)生的機(jī)制研究. 2011年國(guó)家自然科學(xué)基金青年項(xiàng)目；

5. 非神經(jīng)細(xì)胞對(duì)背根神經(jīng)節(jié)神經(jīng)細(xì)胞內(nèi)P物質(zhì)釋放的調(diào)控機(jī)制。2010年國(guó)家自然科學(xué)基金面上項(xiàng)目；