個(gè)人簡(jiǎn)介

職稱(chēng)：教授

民族：漢族

學(xué)科專(zhuān)業(yè)：有機(jī)化學(xué)、藥物化學(xué)

研究方向：1）藥物化學(xué)導(dǎo)向的有機(jī)合成方法學(xué)研究；

2）過(guò)渡金屬催化合成反應(yīng)；

3）不對(duì)稱(chēng)合成。

辦公室：藥學(xué)院13-428

電子郵箱：[email protected]; [email protected]

熱忱歡迎有機(jī)化學(xué)、藥物化學(xué)及相關(guān)專(zhuān)業(yè)優(yōu)秀學(xué)生報(bào)考本課題組研究生，同時(shí)歡迎優(yōu)秀的本科生加入課題組交流學(xué)習(xí)。

 

學(xué)習(xí)經(jīng)歷

2010.09-2015.06：華東理工大學(xué)，有機(jī)化學(xué)，理學(xué)博士（碩博連讀），導(dǎo)師：施敏 教授/研究員

2011.08-2015.06：中國(guó)科學(xué)院上海有機(jī)化學(xué)研究所，聯(lián)合培養(yǎng)博士，導(dǎo)師：施敏 教授/研究員

2006.09-2010.06：湖北大學(xué)，應(yīng)用化學(xué)，理學(xué)學(xué)士

 

工作經(jīng)歷

2024.03-至今：中南民族大學(xué)，藥學(xué)院（教授、碩士生導(dǎo)師）

2018.11-2024.03：中南民族大學(xué)，藥學(xué)院（副教授、碩士生導(dǎo)師）

2016.06-2018.06：西班牙加泰羅尼亞化學(xué)研究所，歐盟“瑪麗居里”學(xué)者計(jì)劃 (博士后項(xiàng)目)，導(dǎo)師：Antonio M. Echavarren 教授

2015.07-2016.05：上海藥明康德新藥開(kāi)發(fā)有限公司，管理培訓(xùn)生

 

承擔(dān)項(xiàng)目與課題

（1）國(guó)家自然科學(xué)基金青年項(xiàng)目（No. 22101303）2022-2024 主持

（2）湖北省自然科學(xué)基金面上項(xiàng)目（No. 2023AFB664）2023-2025 主持

（3）中央高校基本科研業(yè)務(wù)費(fèi)專(zhuān)項(xiàng)資金重點(diǎn)項(xiàng)目（No.CZZ24006）2024-2026 主持

（4）中南民族大學(xué)引進(jìn)人才科研啟動(dòng)基金重點(diǎn)項(xiàng)目（No. YZZ18009）2019-2023 主持，已結(jié)題

（5）科技部外國(guó)文教專(zhuān)家項(xiàng)目（No. G2022185002L）2022.1-2023.12 主持，已結(jié)題

（6）湖北省自然科學(xué)基金面上項(xiàng)目（No. 2020CFB250）2020-2022 主持，已結(jié)題

（7）科技部外國(guó)文教專(zhuān)家項(xiàng)目（No. G20200017117）2020.1-2020.12 主持，已結(jié)題

（8）中央高?；究蒲袠I(yè)務(wù)費(fèi)專(zhuān)項(xiàng)資金項(xiàng)目（No.CZQ19014）2019-2020 主持，已結(jié)題

（9）歐洲研究理事會(huì)（ERC）“瑪麗居里”學(xué)者計(jì)劃（No.702524）2016-2018 主持，已結(jié)題

 

主要獲獎(jiǎng)及榮譽(yù)

2025年第八屆“十佳青年教工”

2024-2025學(xué)年度“五四青年（教工）先鋒”

2021-2022學(xué)年“優(yōu)秀班導(dǎo)師”

2018年入選湖北省高層次人才計(jì)劃

2016年入選歐盟“瑪麗居里”學(xué)者計(jì)劃

2014年獲得博士研究生國(guó)家獎(jiǎng)學(xué)金

 

學(xué)術(shù)兼職

中國(guó)化學(xué)會(huì)/美國(guó)化學(xué)會(huì)會(huì)員，受邀擔(dān)任國(guó)際學(xué)術(shù)期刊Organic Letters、Chemical Communications、Advanced Synthesis & Catalysis、The Journal of Organic Chemistry、Bioconjugate Chemistry、Current Topics in Medicinal Chemistry、Current Organic Chemistry審稿人。

 

論文成果

(1)   Xiang Huang, Jin-Ming Yang.* Lewis Acid-Catalyzed Intramolecular Cyclization of 7-Alkynylcycloheptatrienes with Carbonyls: Access to 3,4-Disubstituted 2,5-Dihydropyrroles. Chemical Communications, 2025, 61, 9686-9689. (SCI二區(qū)期刊，Nature指數(shù)收錄)

(2)   Ze Zhou, Xiang Huang, Qing-Yi Wei, Yi-Lin Wang, Bin Wu, Jin-Ming Yang.*. Access to Piperazine-Fused Pyrrolocarbazoles Enabled by Acid-Catalyzed Stereoselective Hydroarylation of Ynamide-Indoles and Subsequent Diels-Alder Reactions/Aromatizations. Organic Letters, 2024, 26, 7273–7278. (SCI一區(qū)top期刊，Nature指數(shù)收錄)

(3)   Jin-Ming Yang,* Guang-Chao Feng, Xiang Huang, Yi-Lin Wang, Qing-Yi Wei, Bin Wu.* Rhodium(III)-Catalyzed Intramolecular Cyclization and Sequential Aromatization of Ynamides with Propargyl Esters: Access to 2,5-Dihydropyrroles and Pyrroles. Organic Letters, 2024, 26, 6191-6196. (SCI一區(qū)top期刊，Nature指數(shù)收錄)

(4)   Xin-Yu Yang,^§ Jin-Ming Yang,^§* Bin Wu.* TMSOTf-Promoted Cyclization of Indole-2-methyl-a-aminoketones: Access to 4-Aryl-Substituted b-Carbolines. Organic Letters, 2024, 26, 1105-1109. (§共同一作，SCI一區(qū)top期刊，Nature指數(shù)收錄)

(5)   Guang-Chao Feng,^? Jun-Chi Li,^? Xiang Huang, Ji-Kai Liu, Bin Wu, Jin-Ming Yang.* Cascade Hydroarylation/Diels-Alder Cycloaddition of Alkynylindoles with Electron-Deficient Alkynes and Alkenes. Chemical Communications, 2024, 60, 328-331. (?共同一作，SCI二區(qū)top期刊，Nature指數(shù)收錄)

(6)   Qing-Yi Wei,^? Ze Zhou,^? Meng-Lian Yao,^? Ji-Kai Liu, Bin Wu, Jin-Ming Yang.* Rhodium(III)-Catalyzed Intermolecular [3+3] Annulation of Benzoxazines with Quinone Compounds: Access to Spiro-Heterocyclic Scaffolds. Chemical Communications, 2023, 59, 11520-11523. (?共同一作，SCI二區(qū)top期刊，Nature指數(shù)收錄)

(7)   Meng-Lian Yao, Xiao-Yuan Wang, Guang-Chao Feng, Ji-Kai Liu, Bin Wu,* Jin-Ming Yang.* Palladium(II)-Catalyzed Intramolecular [2 + 2 + 2] Annulation of Indolyl 1,3-Diynes: Construction of Azepino-Fused Carbazoles. Organic Letters, 2023, 25, 4615-4620. (SCI一區(qū)top期刊，Nature指數(shù)收錄)

(8)   Jin-Ming Yang,* Meng-Lian Yao, Jun-Chi Li, Ji-Kai Liu, Bin Wu.* Access to Azepino-annulated Benzo[c]carbazoles Enabled by Gold-Catalyzed Hydroarylation of Alkynylindoles and Subsequent Oxidative Cyclization. Organic Letters, 2022, 24, 6505-6509. (SCI一區(qū)top期刊，Nature指數(shù)收錄)

(9)   Zhe Fan,^{^} Shao-Fei Ni,^{^} Jin-Yu Pang, Li-Ting Guo, Hao Yang, Ke Li, Cheng Ma, Ji-Kai Liu,* Bin Wu,* Jin-Ming Yang.* Cu(I)-catalyzed cross-coupling rearrangements of terminal alkynes with tropylium tetrafluoroborate: Facile access to barbaralyl substituted allenyl acid esters and 7-alkynyl cycloheptatrienes. The Journal of Organic Chemistry, 2022, 87, 3066-3078. (SCI二區(qū)top期刊)

(10)            Inmaculada Martín-Torres, Gala Ogalla, Jin-Ming Yang, Antonia Rinaldi, Antonio M. Echavarren*. Enantioselective alkoxycyclization of 1,6-enynes with gold(I)-cavitands: Total synthesis of Mafaicheenamine C. Angewandte Chemie International Edition, 2021, 60, 9339-9344. (SCI一區(qū)top期刊，Nature指數(shù)收錄，入選Top Downloaded Article，IF2021: 15.336)

(11)            Jin-Ming Yang, Cheng-Zhi Zhu, Xiang-Ying Tang,* Min Shi*. Rhodium(II)-catalyzed intramolecular annulation of 1-sulfonyl-1,2,3-triazoles with pyrrole and indole rings: facile synthesis of N-bridgehead azepine skeletons. Angewandte Chemie International Edition, 2014, 53, 5142-5146. (SCI一區(qū)top期刊，Nature指數(shù)收錄，入選ESI高引用論文，已引用163次，IF2014: 11.261)

(12)            Jin-Ming Yang, Peng-Hua Li, Yin Wei, Xiang-Ying Tang,* Min Shi*. Gold(I)-catalyzed highly stereoselective synthesis of polycyclic indolines: construction of four contiguous stereocenters. Chemical Communications, 2016, 52, 346-349. (SCI一區(qū)top期刊, Nature指數(shù)收錄)

(13)            Jin-Ming Yang, Xiang-Ying Tang,* Min Shi*. Gold(I)-catalyzed intramolecular cycloisomerization of propargylic esters with furan rings. Chemistry – A European Journal, 2015, 21, 4534-4540. (SCI二區(qū)top期刊)

(14)            Jin-Ming Yang, Xiang-Ying Tang, Yin Wei,* Min Shi*. Phosphine-promoted cyclization of dicyclopropenones. Advanced Synthesis & Catalysis, 2013, 355, 3545-3552. (SCI二區(qū)top期刊)

(15)            Jin-Ming Yang, Zhen Zhang, Yin Wei,* Min Shi*. Silver(I)-catalyzed tandem reactions of N-activated aziridine-propargylic esters to pyrrolidin-3-one derivatives. Tetrahedron Letters, 2012, 53, 6173-6176. (SCI三區(qū))

(16)            Jin-Ming Yang, Rui Zhang, Wen-Feng Wang, Zhen Zhang, Min Shi*. Axially chiral N-heterocyclic carbene gold(I) complex catalyzed asymmetric Friedel-Crafts/cyclization reaction of nitrogen-tethered 1,6-enynes with indole derivatives. Tetrahedron Asymmetry 2011, 22, 2029-2038. (SCI三區(qū))

(17)            Wen-Feng Wang, Jin-Ming Yang, Fei-Jun Wang, Min Shi*. Axially chiral N-heterocyclic carbene gold(I) complex catalyzed asymmetric cycloisomerization of 1,6-enynes. Organometallics 2011, 30, 3859-3869. (SCI二區(qū))

(18)            Peng-Hua Li, Jin-Ming Yang, Yin Wei,* Min Shi*. Silver(I)-catalyzed intramolecular cyclizations of epoxide-propargylic esters to 1,4-oxazine derivatives. ChemistryOpen 2017, 6, 21-24. (SCI三區(qū))

 

專(zhuān)利

(1)   楊金明，姚夢(mèng)蓮，吳濱，一種稠環(huán)吲哚類(lèi)化合物及其制備方法和應(yīng)用，授權(quán)日期：2024.02.27，授權(quán)專(zhuān)利號(hào)：ZL202210679227.8，發(fā)明專(zhuān)利，中國(guó)。

(2)   楊金明，李俊馳，一種稠環(huán)氫化異喹啉化合物及其制備方法和應(yīng)用，申請(qǐng)?zhí)柣驅(qū)＠?hào)：202310955290.4，申請(qǐng)日期：2023.7.31，發(fā)明專(zhuān)利，中國(guó)。

(3)   楊金明，李俊馳，吳濱，封廣超，黃翔，一種稠環(huán)奧苷菊環(huán)類(lèi)化合物及其制備方法，申請(qǐng)?zhí)柣驅(qū)＠?hào)：202310955283.4，申請(qǐng)日期：2023.7.31，發(fā)明專(zhuān)利，中國(guó)。