姓名:熊海容
職務(wù)/職稱(chēng):教授,博導(dǎo)
研究專(zhuān)長(zhǎng):極端微生物,酶工程
通訊地址:中南民族大學(xué)生科院B407
聯(lián)系電話(huà):027-67842689
E-mail:xionghr@mail.scuec.edu.cn
一、學(xué)習(xí)及工作簡(jiǎn)歷
2006.10-至今,中南民族大學(xué)生命科學(xué)學(xué)院,教授
2004.12-2006.10,香港科技大學(xué)海洋海岸實(shí)驗(yàn)室,副研究員;
2001.06-2004.11,芬蘭赫爾辛基工業(yè)大學(xué),生物工程專(zhuān)業(yè),博士;
二、主要社會(huì)兼職
湖北省飼料工業(yè)協(xié)會(huì)專(zhuān)家委員會(huì)委員;
湖北省微生物學(xué)會(huì)酶工程專(zhuān)業(yè)委員會(huì)常務(wù)委員;
中華預(yù)防醫(yī)學(xué)會(huì)消毒分會(huì)教育科普學(xué)組委員;
湖北省食品科學(xué)技術(shù)學(xué)會(huì)常務(wù)理事
三、科研活動(dòng)及成果
(一)主要研究方向
極端微生物,酶工程
(二)主持的縱向科研項(xiàng)目
1.2018ABA093,湖北省技術(shù)創(chuàng)新專(zhuān)項(xiàng)重大項(xiàng)目,微生物綜合利用秸稈資源關(guān)鍵技術(shù)研發(fā),2018.01-2020.12,主持,200萬(wàn)。
2.2020BGB009,湖北省科技計(jì)劃項(xiàng)目援疆援藏類(lèi),玉米秸稈飼料化利用關(guān)鍵技術(shù),2020.01-2022.12,主持,30萬(wàn)。
3.第七批東湖國(guó)家高新區(qū)“3551人才計(jì)劃”入選者,工業(yè)酶的分子改良與產(chǎn)品研制,2014.01-2016.12,主持,100萬(wàn)元
(三)科研成果及榮譽(yù)
1.2022年湖北省科技進(jìn)步二等獎(jiǎng)(排名第一):飼用耐熱半纖維素酶的分子改良與產(chǎn)業(yè)化應(yīng)用(2022J-208-2-079-010)
2.2020年中國(guó)輕工業(yè)聯(lián)合會(huì)科技進(jìn)步三等獎(jiǎng)(排名第一):耐熱飼用酶制劑的基因改良和產(chǎn)品研制(2020-J-3-24)
3.2016年湖北省科技進(jìn)步三等獎(jiǎng)(排名第一):耐熱飼料用酶的基因優(yōu)化和高產(chǎn)工程菌構(gòu)建(2016J-232-3-122-016)
(四)代表性論文
1.Xiong H,Weymarn N, Leisola M, Turunen O. Influence of pH on the production of xylanases byTrichoderma reeseiRut C-30.Proc Biochem.2004; 39:729-733
2.XiongH,Turunen O,Pastinen O, Leisola M, Weymarn N.Improved xylanase production byTrichoderma reeseigrown on L-arabinose and lactose or D-glucose mixtures.Appl Microbiol Biotechnol.2004; 64:353-358
3.Xiong H,Fenel F, Leisola M, Turunen O. Engineering the thermostability ofTrichoderma reeseiendo-β-1,4 xylanase II by combination of disulphide bridges.Extremophiles.2004; 8: 393-400
4.Xiong H*,Nyyss?l? A, J?nis J, Pastinen O, Weymarn N, Leisola M, Turunen O. Characterization of the xylanase produced on submerged cultivation byThermomyces lanuginosusDSM 10635.Enzyme Microb Technol.2004; 35: 93-99
5.Xiong H,Weymarn N, Turunen O, Leisola M, Pastinen O. Xylanase production byTrichoderma reeseiRut C-30 grown on L-arabinose-rich plant hydrolysates.Biores Technol.2005; 96: 753-759
6.Xiong H,Song L, Xu Y, Tsoi MY, Dobretsov S, Qian PY. Characterization of proteolytic bacteria from the Aleutian deep-sea and their proteases.J Ind Microbiol Biotechnol.2007; 34:63-71
7.Xiong H,QiSH, Xu Y, Miao L,Qian PY.Antibiotic and antifouling compound production by themarine-derivedfungusCladosporiumsp. F14.JHydro-environment Research.2009; 2:264-270
8.Wang YW,Fu Z, Huang HQ, Zhang HS, Yao B,Xiong H*, Turunen O.Improvedthermal performanceofThermomyces lanuginosusGH-11xylanaseby engineering of an N-terminal disulfide bridge.Biores Technol.2012,112:275-279
9.Yu T, AnbarasanS, Wang Y, Telli K,...Turunen O,Xiong H*.HyperthermostableThermotoga maritimaxylanase XYN10B shows high activity at high temperatures in the presence of biomass-dissolving hydrophilic ionic liquids.Extremophiles.2016, 20:515-524
10.WangY, Shu T, Fan P, Zhang H, Turunen O,Xiong H*, Yu L.Characterization of a recombinant alkaline thermostable β-mannanase and itsapplication in eco-friendly ramie degumming.Proc Biochem.2017, 61:73-79
11.WangY,Bai Y,Shu T,Peng Y,Zhang H, Turunen O,Xiong H*, Yu L.Characterization of a versatile glycoside hydrolase Cel5M fromPectobacterium carotovorumHG-49 for ramie degumming.TextResJ.2020, 90:1602-1615
12.Wang W,Wang H,Zhao Z, Huang X,Xiong H*, Mei Z.Thymol activates TRPM8-mediated Ca2+ influx for its antipruritic effectsand alleviates inflammatory response in Imiquimod-induced mice.ToxicolApplPharm.2020, 407:114247
13.Zhao P, Zhang M, Wan X, Geng P,Xiong H*, Hu X.A novel Co2+-dependent Leucyl aminopeptidase Amp0279 originated fromLysinibacillus sphaericusand heterologous expression using different expression systems.Appl Microbiol Biotechnol.2022, 106:1139-1149
14.WangY, WangJ, ZhangZ, YangJ, Turunen O,Xiong H*.High-temperature behavior of hyperthermostableThermotoga maritimaxylanase XYN10B after designed and evolved mutations.Appl Microbiol Biotechnol.2022, 106:2017-2027
15.Wang Y, Zhao P, Zhou Y, Hu X,Xiong H*.From bitter to delicious: Properties and Uses of Microbial Aminopeptidases.World JMicrobiolBiotechnol.2023, 39(3):72
四、教學(xué)活動(dòng)及成果
(一)承擔(dān)課程(本科生、研究生)
承擔(dān)《生物工程設(shè)備》的本科教學(xué),承擔(dān)《生物與醫(yī)藥進(jìn)展》的研究生教學(xué)。
(二)教學(xué)成果及榮譽(yù)
多次指導(dǎo)本科生獲得湖北省優(yōu)秀論文獎(jiǎng)
五、社會(huì)服務(wù)活動(dòng)及其成果
成果與專(zhuān)利:
1.發(fā)明專(zhuān)利授權(quán)號(hào)ZL202010447518.5:一種極端耐熱木聚糖酶XYNA及其突變體基因、應(yīng)用和制備方法,熊海容,王晶 授權(quán)日:20211126
2.發(fā)明專(zhuān)利授權(quán)號(hào)ZL202010447957.6:一種低溫下高酶活的耐熱木聚糖酶XYNB及其突變體基因、應(yīng)用和基因序列制備方法,熊海容,王晶 授權(quán)日:20211019
3.發(fā)明專(zhuān)利授權(quán)號(hào)ZL201810101054.5:一種極端耐熱木聚糖酶1VBR的突變體XYNH及其用途,熊海容,授權(quán)日:20200505
4.發(fā)明專(zhuān)利授權(quán)號(hào)ZL201810101058.3:一種極端耐熱木聚糖酶1VBR的突變體XYNR及其用途,熊海容,授權(quán)日:20200505